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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '718e6d610c0876363f67a800c5350cc12fc51d13d1b2d82bb32da371d715fe94' 
  AND token = 'Y3gIq/xg5tpWg/kYAgvc0Tt/wiygrB+uSpQqpI+7qtI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}