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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '435260987de46f2dabc7e8511c938f0a104d465d6d7c890b3d9f48b2da2aabe0' 
  AND token = 'sc3dPEynu1HiBhUZ+t0JtgnO5qc8yY7aRngil2QhJPM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}