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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '15c1db7d60ef3fd3e3967b0681d3c8a8ea4289f310794b2949e1218db0166e24' 
  AND token = 'i3Z1sJAyHEvsJup1IOnk7DuKYldoGu9y9XHAcEN29xw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}