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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd0b432fb753612388436ecbd8a16c76333dc7944c328a00ad29fce50761dc148' 
  AND token = 'HbH2dp3bJPDLmxH2Zg2yiQgCsNG/1/XMRX1/mf0iyIg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}