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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6d6904460dfeee9b72f30e64228ea15fe9e6728cf6ce3515da7b57c8b653bdbf' 
  AND token = 'HhtZnQhF8Fkue1wTW68gyGy0I4ASLl8icR4S7kW2rN0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}