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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b59c97d75fad1821b8ec595c55439224f171afade0f43c924c0b7dcb1f7f583d' 
  AND token = 'PpCf7S7AO2MGlYqHZy/7PK1pZCl9GRtsWe5UtqohAmI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}