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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'fe6a043247fe778fcd1b884df007ffae9201c659d291d01a484caab21ac7b582' 
  AND token = '6UfLT3tHWgLDnfyoDkBvqpqwDpivvHRyIUI2XZe0NU4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}