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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c834fe0d8976a6c51ca19502c3a78a29904dd171a2bee3a9693587c55d1b0c4f' 
  AND token = 'C+baT6HjdM9aZtElAmg/8M4FiDgmbn2eI0nC4PoIBhU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}