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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '366fa45f3ff011aaf2e5469c18c45a1ce80f7b1ea4a9312642808cd55f20a675' 
  AND token = 'CJS7RjwfGVUyaTm9DWa4WAT0XeXs0cmn9AbBXVoKXfg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00051

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}