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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7485c28550a40fe7ed370a2fe33386d52bc7d877f4981a03c2fd2d1b67b822b9' 
  AND token = 'FuOm2pyOZSMd20w3VTFQ4XN/pWOLOr3OtSVUmkBv1O4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}