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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '44c2bcef5bb885014f17df3957a5863a00988653f4a76f2fe80a7145645883fa' 
  AND token = 'fUxeTiWbs+eGL4dAHl/8YCaUa6f4rZMKUAW0hP3lLek=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}