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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5cc935342999b30ccad11600aec1b8d20d5d41ecff080c0ed5763ee15afeb9e0' 
  AND token = 'O2UihTzBd+E2gmuXdZhsy73twi0O1l9Jq5hQZgHDnJo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}