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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2ae0b54c6271208f184cd4147788fa846bd1f75d698358d9fd62bf826d703ccf' 
  AND token = 'ncYj8hT1MVI2ixs74Qw8ATgRBdHA5aiTMzB0uXbI33A=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}