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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a69fd75106e583f03828d5573ed79d7d7c443f14a15bc196ce965e6632cde685' 
  AND token = '/q5fdPBgKmoB0BXRRlUQCsC5wmPUURmU8j9VUkAc9Pk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}