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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '33d4df22561772aefd1812cd44471687a75f6ad50258cd1c1eb10e54a1be65e7' 
  AND token = 'BBVj0+wAt02R/8vKn5niZpCiQREXrqNRj6X9n2R/wCg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}