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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1ed26c9b2fc99bc1c8aa3d1984bb1eee17609293780ab1023cc81ed426d7f441' 
  AND token = '1+DNH0QJA1kdylAmnUKhM37V+uec4tEjPo0QaHIy3IY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}