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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '647e3005fdd8b84318d3a88364cffb380d2b3d2d984c6560733e673f55cd5434' 
  AND token = '3r9znQQStaBcKd2BtxbNREtVPazEDiWzSz6FD4zKXlE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}