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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4d8eef9dd7e92c70316873dda80873a69e3ad5fa2025f5c3096e76020d9c5230' 
  AND token = 'bU6cqznUCsMeGtWxb83jphOkuWGPWpu9XljbQ+V1VBo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}