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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7438ecbee780a739d565a4b4745624ce75d671b0dc048441575c2ccef4c87a06' 
  AND token = 'oro5exq3rDReROCXw3W6G7uii4+/iPK2Iv78497NlRg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}