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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4052028ce660251409c359e778d9e13bcc409dcbfec48bdf6de9c0a8a01861b1' 
  AND token = 'HSKs6zTPkl+8MzqUDoyVBleHRjyPLPaFoQl1dW4Y/BY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00038

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}