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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '77032a16a714039c2824e18015a7921ae085917458b17472715b1250d4c22c6c' 
  AND token = 'edaZMOLTly/jNDB6IWi/ZSD8BA6ThA1ZAGVvbYT5Tss=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}