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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '764cfa5c7015ead29b3870496ee6b32d66fd0a758306a4c2226753f66bbf3673' 
  AND token = 'oADc+1uk/hD+3rtgCsECXxatKds4m0WzAYa7kbJzLTc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}