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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd075b4e0ca4a81fe519ecb68f5c2cf2ce243def5cf961733577f6ceff8ebec51' 
  AND token = 'dh+qaubwNYRqGw5dwW+kSqrzsEMwXwsfXvja+3k3spM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}