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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7e2c05d5ffa329ba8b2b1dd51e84a029d2e0e5a7d6a02f8e40238d44e856993c' 
  AND token = '1T3vrWdTKCcBRfk/am4oSeRFe6Cz0XrUOdAX/auDdKc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}