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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a4209c9c51c2bb3546b804dd1e9cfc03000211426892b61261e2ed49d592958f' 
  AND token = 'asM9GtuRx7GqEj4F6SW975nzTBP11t8+RdNgfqgN0ek=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}