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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1c6b550bf3eb15ae0de7b7b313fc50f90b5163c99385a8237c9f360acd88af19' 
  AND token = 'DxRCLq5bAf8jdfqbIXQKZoKrCPEvzkZOv71DQ4+84s0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}