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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9d27f8cd644acbaa9b7840ab1b968e14102072f5f7d25a4142eba6f20f3e2a4a' 
  AND token = 'i+hnPygxmW4MEdFyJ71+kSSUmBf7P2qm6VYfcxBURxk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}