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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0448e4c60e91a9c7ff6877b12da0c4f834646eaaf4c5151dafd8e06022c12104' 
  AND token = 'RffjEV9hkxBQbGQBYI52RTD6CgN09Cr5kKTe3i4BKyw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}