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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c543617472ee01d9b3b8db92154dbebb366b90d3ec8f287d3b0f482d9d473766' 
  AND token = 'g27TtCr8tVePnAUKionb9EStQPB5t8AptpXoZxiE0pU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}