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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a1933ec48f2f8450cc1faa41d09640096f090beb3fad72bbab0f9ca04dca6933' 
  AND token = 'NLCEmpe7o72qzItdmWSvnN9GkYJAc/a/+kXXF4VPsks=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}