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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6444d49e728dc3413fcf420e40b31e4281e56af4d1bf29d7bc5ac6590460ce0e' 
  AND token = '5cQ7i21F6S3o6jewTIJXFjvdbV9tKQ6kMBegXypzWAQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00046

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}