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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2ab91fa2eb3ea14450ec158f0c48e09c16363c175780425b88b04b794451159d' 
  AND token = 'jNw/+7mpExxx7b9O1MWlyfQJJnF4xXY7oFx8uuAkqe0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}