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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0781e7f51bed7aa0986fa5788f51056bbaae08753b4196462bec3576748e132c' 
  AND token = 'OYjP9+dk6JBeACpGECZbMxS2sRNxI5hwX4Xx8knfsek=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}