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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6e0180efccc2ae9a65b418ae7aa7c30e960f403b1de435548fc73155a81006a4' 
  AND token = 'lhGQDqtL14qQgH2RLp18Scg4neKHbl/DgLcLwJZ9nt8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}