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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3683e0b304d117b6d09757c8b8a4570caa760ce9d19377bb5d3360237bce4b20' 
  AND token = '59oxsSvT16jxGt/LlQ25nvld9LxqkhPMCZzGVMHRtyk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00049

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}