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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ee565afdad4b56fab678b616804eb55278dcac5bf3002f8f5ea838363c511270' 
  AND token = '8lYkgps2L0+1QzZt1tkQ30D/8lSedFh0xlZ9bFiYfeE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}