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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2e2308241adfaa489bb02579baa2b31fe032d330300f280b3ce75c0c68893598' 
  AND token = 'ILSlFdKWxyCbjyIlPbIn6bHKWE4Ct+PKIiD2k1BDL/I=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}