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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3f62aaae0a3e8c92dfb6965aaf736dae5633975b2a22ab185012bc97ff1969aa' 
  AND token = 'X0I+/kTsUZsv7IN6WPKKK1D9NbYAvM1JX8KtvLVXBh0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}