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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '746af50df8adea75022d8d1daaa5ab26899ca88387cc009d8cb05e2a79426ee8' 
  AND token = '+KDOn1YJp/tSvNzEYBWfq3fXieJHcU0r0b81XrC6lf0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}