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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '055807ebc611176c9f51cbd1acd0d78d8a49e907ad9a6fe75341ee3a01e25b6a' 
  AND token = 'rc9JtvS2lL2gpwkHVFpjA6y9vaUgH9QmnkpNhDGKsJc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}