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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c0fa8d1a787078e28ff6a4b9a791f958f1b25f3920cedd713ef1710b4195652a' 
  AND token = 'IUNA5+0ITpr6BaVJL/0DbCR8xjfzACFcj9rN5atc1bM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}