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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '074ef925f9c4562e08e7d34107e48c48d9f86bf319ad67cbf7eb237ab19369d1' 
  AND token = 'A7Haw/f+dhk6ZMcm0zGEObywbGUpVVOwkpbSHdSMMp8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}