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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e56780fe7e80bd2679b3af2257abdb4336267519b79616b17e040762e7aa3d1e' 
  AND token = 'eTWzSmZKrHqYBQHZHfl7itsqDy9Y+TrgD/LXaYeaBeU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}