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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '215a8826384c05d1910df0615424acce9e9c86e3022e5942020db92d072e1191' 
  AND token = 'gqQ0FkY9h0B7HptFyD+A6ikhTMSAMDFaBcqPUMEBmn0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}