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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a21c6b6e826b973a69fcacd768a2d76a1b2ab690c667913a8eca2ca8f993d343' 
  AND token = 'RY4FKrZACEvxXZARs3CHV9pkPMobgd4J01kTcluq0q4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}