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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a2424967584344a9b857184a662e53e5f64f7e541e7dceddb62183c53ca78ecd' 
  AND token = 'a2ntfed3aKuTDF6mV6nk2GpkjI78FSbua3h/bupBx6U=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}