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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3d37c4dfa2aa514f4b8c63a3d4e53ef4293ae2a456b6b6b1f1dba34f9a901697' 
  AND token = 'GI/4cO/EuBtq23CviNQAxOZ+CUuWaQOpiwHTzCS0dXs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}