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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'fc6b5b1f3995fe412eaa7c78e4fb265d9ac1e6ac378c34b645fe7b69f4685457' 
  AND token = 'PpZtjXYqdp4fKKfhUJX/7uiBbwIMqnT3IWE3YrN1Ab4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}