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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e2a4d85b30b1657e7969bdef5615137276cde46c8705433353e7a3edd942b369' 
  AND token = 'cnTKCSGdoSIRZOqIqTd/QPGuGkwHWuV1ybVAE/kkpoo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00046

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}