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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'de3ca6c1e0d46d6d895fa44dbc46180e9352f74e52df5b06eb84917fd0917799' 
  AND token = 'EVD0xGx0bbKrivQo52nrwdygjIy665ZbNzURxp/A7gk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}